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The association between HIV (treatment), pregnancy serum lipid concentrations and pregnancy outcomes: a systematic review.


ABSTRACT:

Background

Observed adverse effects of antiretroviral therapy (ART) on the lipid profile could be of significance in pregnancy. This systematic review aims to summarize studies that investigated the association between HIV, ART and serum lipids during pregnancy and adverse pregnancy outcomes.

Methods

A systematic search was conducted in five electronic databases to obtain articles that measured serum lipid concentrations or the incidence of dyslipidaemia in HIV-infected pregnant women. Included articles were assessed for quality according to the Cochrane Risk of Bias Tool. The extracted data was analysed through descriptive analysis.

Results

Of the 1264 articles screened, 17 articles were included in this review; eleven reported the incidence of dyslipidaemia, and twe

SUBMITTER: Harmsen MJ 

PROVIDER: S-EPMC5505132 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature