Comparative genomic analysis of Acinetobacter strains isolated from murine colonic crypts.

ABSTRACT:

Background

A restricted set of aerobic bacteria dominated by the Acinetobacter genus was identified in murine intestinal colonic crypts. The vicinity of such bacteria with intestinal stem cells could indicate that they protect the crypt against cytotoxic and genotoxic signals. Genome analyses of these bacteria were performed to better appreciate their biodegradative capacities.

Results

Two taxonomically different clusters of Acinetobacter were isolated from murine proximal colonic crypts, one was identified as A. modestus and the other as A. radioresistens. Their identification was performed through biochemical parameters and housekeeping gene sequencing. After selection of one strain of each cluster (A. modestus CM11G and A. radioresistens CM38.2), comparative genomic analy

SUBMITTER: Saffarian A 

PROVIDER: S-EPMC5505149 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature