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Pattern classification of endocervical adenocarcinoma: reproducibility and review of criteria.


ABSTRACT: Previously, our international team proposed a three-tiered pattern classification (Pattern Classification) system for endocervical adenocarcinoma of the usual type that correlates with nodal disease and recurrence. Pattern Classification-A tumors have well-demarcated glands lacking destructive stromal invasion or lymphovascular invasion, Pattern Classification-B tumors show localized, limited destructive invasion arising from A-type glands, and Pattern Classification-C tumors have diffuse destructive stromal invasion, significant (filling a 4 × field) confluence, or solid architecture. Twenty-four cases of Pattern Classification-A, 22 Pattern Classification-B, and 38 Pattern Classification-C from the tumor set used in the original description were chosen using the reference diagnosis origi

SUBMITTER: Rutgers JK 

PROVIDER: S-EPMC5506840 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature