Efficiency data of intracellular recombinant protein delivery using cationic lipid coated silk fibroin particle.

ABSTRACT: This article presents data related to the research article "Fibroin particle-supported cationic lipid layers for highly efficient intracellular protein delivery" and focuses on the delivery efficiency aspects of the fibroin particle-cationic lipid complex (Fibroplex), including its fabrication and the intracellular delivery to the mouse skin tissue. We introduced a stable lipid-particle complex called "Fibroplex", formed by loading cargo protein onto a silk fibroin spherical particle core complexed with cationic liposomes to address the intracellular recombinant protein delivery. This system exhibits cationic charge, which is advantageous for cellular uptake. The particle core is loaded with the cargo protein with high efficiency and shows long-term release in serum environment. Fibroplex

SUBMITTER: Kim WJ 

PROVIDER: S-EPMC5506864 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature