The prognostic and clinicopathologic characteristics of CD147 and esophagus cancer: A meta-analysis.

ABSTRACT:

Objective

The prognostic significance of CD147 expression in esophageal cancer patients remains controversial. Using a meta-analysis, we investigated the prognostic and clinicopathologic characteristics of CD147 in esophageal cancer.

Methods

A comprehensive literature search of the PubMed (1966-2016), EMBASE (1980-2016), Cochrane Library (1996-2016), Web of Science (1945-2016), China National Knowledge Infrastructure (1982-2016), and Wanfang databases (1988-2016) was performed to identify studies of all esophageal cancer subtypes. Correlations between CD147 expression and survival outcomes and clinicopathological features were analyzed using meta-analysis methods.

Results

Seventeen studies were included. High CD147 expression reduced the 3-year survival rate (OR = 3.2

SUBMITTER: Li H 

PROVIDER: S-EPMC5507401 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature