Smoking during pregnancy in relation to grandchild birth weight and BMI trajectories.

ABSTRACT:

Background

Maternal smoking has been linked to lower birth weight and higher risk of childhood obesity. However, it is unknown whether grand-maternal smoking during pregnancy is associated with grandchildren birth weight and body mass index (BMI) trajectories.

Methods

We investigated associations of smoking during pregnancy with birth weight, risks of overweight and BMI trajectories among 46,858 mother-child dyads and 6,583 grandmother-mother-child triads of three cohort studies of related individuals. Smoking during pregnancy was reported by mothers, and anthropometric data were provided by participants in each cohort.

Results

Compared to grandchildren of non-smoking women, grandchildren of women who smoked more than 14 cigarettes per day throughout pregnancy were 70

SUBMITTER: Ding M 

PROVIDER: S-EPMC5507479 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature