Paroxysmal Dyskinesia in Border Terriers: Clinical, Epidemiological, and Genetic Investigations.

ABSTRACT:

Background

In the last decade, a disorder characterized by episodes of involuntary movements and dystonia has been recognized in Border Terriers.

Objectives

To define clinical features of paroxysmal dyskinesia (PD) in a large number of Border Terriers and to study the genetics of the disease.

Animals

110 affected and 128 unaffected client-owned Border Terriers.

Methods

A questionnaire regarding clinical characteristics of PD was designed at Utrecht University and the University of Helsinki. Thirty-five affected Border Terriers underwent physical examination and blood testing (hematology and clinical biochemistry). Diagnostic imaging of the brain was performed in 17 affected dogs and electroencephalograms (EEG) between episodes were obtained in 10 affected dogs.

SUBMITTER: Stassen QEM 

PROVIDER: S-EPMC5508305 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature