Hyperfibrinolysis and Hypofibrinogenemia Diagnosed With Rotational Thromboelastometry in Dogs Naturally Infected With Angiostrongylus vasorum.

ABSTRACT:

Background

The pathomechanism of Angiostrongylus vasorum infection-associated bleeding diathesis in dogs is not fully understood.

Objective

To describe rotational thromboelastometry (ROTEM) parameters in dogs naturally infected with A. vasorum and to compare ROTEM parameters between infected dogs with and without clinical signs of bleeding.

Animals

A total of 21 dogs presented between 2013 and 2016.

Methods

Dogs with A. vasorum infection and ROTEM evaluation were retrospectively identified. Thrombocyte counts, ROTEM parameters, clinical signs of bleeding, therapy, and survival to discharge were retrospectively retrieved from patient records and compared between dogs with and without clinical signs of bleeding.

Results

Evaluation by ROTEM showed hyperfibr

SUBMITTER: Sigrist NE 

PROVIDER: S-EPMC5508311 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature