Temporal dynamics of neurogenomic plasticity in response to social interactions in male threespined sticklebacks.

ABSTRACT: Animals exhibit dramatic immediate behavioral plasticity in response to social interactions, and brief social interactions can shape the future social landscape. However, the molecular mechanisms contributing to behavioral plasticity are unclear. Here, we show that the genome dynamically responds to social interactions with multiple waves of transcription associated with distinct molecular functions in the brain of male threespined sticklebacks, a species famous for its behavioral repertoire and evolution. Some biological functions (e.g., hormone activity) peaked soon after a brief territorial challenge and then declined, while others (e.g., immune response) peaked hours afterwards. We identify transcription factors that are predicted to coordinate waves of transcription associated with di

SUBMITTER: Bukhari SA 

PROVIDER: S-EPMC5509087 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature