Association of insulin resistance with near peak bone mass in the femur and lumbar spine of Korean adults aged 25-35: The Korean National Health and Nutrition Examination Survey 2008-2010.

ABSTRACT:

Objective

This study aimed to evaluate the relationship between insulin resistance and the bone mineral density (BMD) of femur and lumbar spine in Korean adults who are expected to exhibit near peak bone mass.

Methods

Data from the Korean National Health and Nutrition Examination Survey 2008-2010 were analyzed. A total of 2,750 participants aged 25-35 years were included. Insulin resistance was assessed using a homeostatic model assessment of insulin resistance (HOMA-IR) and serum fasting insulin.

Results

In a multivariate linear regression analysis, the HOMA-IR was significantly inversely associated with the BMD of the total hip (TH, β = -0.052, P = 0.002), femoral neck (FN, β = -0.072, P<0.001), femoral trochanter (FTr, β = -0.055, P = 0.003), femoral intertrochante

SUBMITTER: Choo MS 

PROVIDER: S-EPMC5509105 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature