Role of biomarkers in early infectious complications after lung transplantation.

ABSTRACT:

Background

Infections and primary graft dysfunction are devastating complications in the immediate postoperative period following lung transplantation. Nowadays, reliable diagnostic tools are not available. Biomarkers could improve early infection diagnosis.

Methods

Multicentre prospective observational study that included all centres authorized to perform lung transplantation in Spain. Lung infection and/or primary graft dysfunction presentation during study period (first postoperative week) was determined. Biomarkers were measured on ICU admission and daily till ICU discharge or for the following 6 consecutive postoperative days.

Results

We included 233 patients. Median PCT levels were significantly lower in patients with no infection than in patients with Infection

SUBMITTER: Suberviola B 

PROVIDER: S-EPMC5509107 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature