Predicting in-hospital death during acute presentation with pulmonary embolism to facilitate early discharge and outpatient management.

ABSTRACT:

Background

Pulmonary embolism continues to be a significant cause of death. The aim was to derive and validate a risk prediction model for in-hospital death after acute pulmonary embolism to identify low risk patients suitable for outpatient management.

Methods

A confirmed acute pulmonary embolism database of 1,426 consecutive patients admitted to a tertiary-center (2000-2012) was analyzed, with odd and even years as derivation and validation cohorts respectively. Risk stratification for in-hospital death was performed using multivariable logistic-regression modelling. Models were compared using receiver-operating characteristic-curve and decision curve analyses.

Results

In-hospital mortality was 3.6% in the derivation cohort (n = 693). Adding day-1 sodium and bicarbo

SUBMITTER: Lau JK 

PROVIDER: S-EPMC5509112 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature