Cerebral 18F-FDG PET in macrophagic myofasciitis: An individual SVM-based approach.

ABSTRACT:

Introduction

Macrophagic myofasciitis (MMF) is an emerging condition with highly specific myopathological alterations. A peculiar spatial pattern of a cerebral glucose hypometabolism involving occipito-temporal cortex and cerebellum have been reported in patients with MMF; however, the full pattern is not systematically present in routine interpretation of scans, and with varying degrees of severity depending on the cognitive profile of patients. Aim was to generate and evaluate a support vector machine (SVM) procedure to classify patients between healthy or MMF 18F-FDG brain profiles.

Methods

18F-FDG PET brain images of 119 patients with MMF and 64 healthy subjects were retrospectively analyzed. The whole-population was divided into two groups; a training set (100 MMF, 44 h

SUBMITTER: Blanc-Durand P 

PROVIDER: S-EPMC5509294 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature