Spatiotemporal alignment of in utero BOLD-MRI series.

ABSTRACT:

Purpose

To present a method for spatiotemporal alignment of in-utero magnetic resonance imaging (MRI) time series acquired during maternal hyperoxia for enabling improved quantitative tracking of blood oxygen level-dependent (BOLD) signal changes that characterize oxygen transport through the placenta to fetal organs.

Materials and methods

The proposed pipeline for spatiotemporal alignment of images acquired with a single-shot gradient echo echo-planar imaging includes 1) signal nonuniformity correction, 2) intravolume motion correction based on nonrigid registration, 3) correction of motion and nonrigid deformations across volumes, and 4) detection of the outlier volumes to be discarded from subsequent analysis. BOLD MRI time series collected from 10 pregnant women during 3

SUBMITTER: Turk EA 

PROVIDER: S-EPMC5509493 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature