Visual function quality of life measure changes upon conversion to neovascular age-related macular degeneration in second eyes.

ABSTRACT:

Purpose

To determine changes in quality of life measures when choroidal neovascularization (CNV) developed in the second eye of patients with initially unilateral neovascular age-related macular degeneration (AMD).

Methods

We analyzed responses to the 39-item National Eye Institute Visual Function Questionnaire (NEI-VFQ), 36-item Short Form Health Survey (SF-36), and Hospital Anxiety and Depression Scale (HADS) at baseline, and prior to and following second eye CNV diagnosis in 92 participants enrolled in two Submacular Surgery Trials. Paired t-tests for sample sizes over 30 and Wilcoxon signed-rank tests for sample sizes <30 were performed to compare scores.

Results

CNV development resulted in statistically and clinically significant changes in responses to 20 of 39

SUBMITTER: Paulus YM 

PROVIDER: S-EPMC5511091 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature