Ontology highlight
ABSTRACT:
SUBMITTER: Ancey PB
PROVIDER: S-EPMC5511103 | biostudies-literature | 2017 Jul
REPOSITORIES: biostudies-literature
Stem cell reports 20170622 1
Understanding the processes that govern liver progenitor cell differentiation has important implications for the design of strategies targeting chronic liver diseases, whereby regeneration of liver tissue is critical. Although DNA methylation (5mC) and hydroxymethylation (5hmC) are highly dynamic during early embryonic development, less is known about their roles at later stages of differentiation. Using an in vitro model of hepatocyte differentiation, we show here that 5hmC precedes the express ...[more]