Value of ^99mTc-MDP SPECT/CT and ¹⁸F-FDG PET/CT scanning in the evaluation of malignantly transformed fibrous dysplasia.

ABSTRACT: Although fibrous dysplasia is not considered a potentially premalignant disorder, malignant transformation occurs. Because of its rarity, radiographic features of malignantly transformed fibrous dysplasia on cross-sectional imaging modalities are less recognized, making diagnosis and differential diagnosis of the disease quite difficult in clinical practice. In this study, we analyzed the clinical characteristics, imaging features, pathology findings and surgery strategies of 19 malignantly transformed fibrous dysplasia. We found that there was significant male predominance in this specific cohort (13/6). While osteosarcoma (63.2%) was the most frequently occurring neoplasm secondary to fibrous dysplasia, other less commonly malignantly changed types included fasciculated sarcoma, malignan

SUBMITTER: Wei WJ 

PROVIDER: S-EPMC5511119 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature