Cancer incidence among capacitor manufacturing workers exposed to polychlorinated biphenyls.

ABSTRACT:

Background

We evaluated cancer incidence in a cohort of polychlorinated biphenyl (PCB) exposed workers.

Methods

Incident cancers, identified using state registries, were compared to those in a national population using standardized incidence ratios. Trends in prostate cancer incidence with cumulative PCB exposure were evaluated using standardized rate ratios and Cox regression models. For selected sites, cumulative PCB exposure was compared between aggressive (fatal/distant stage) and localized/regional cancers.

Results

We identified 3,371 invasive first primary cancer diagnoses among 21,317 eligible workers through 2007. Overall relative incidence was reduced. Elevations were only observed for respiratory cancers and among women, urinary organ cancers. Among men, pro

SUBMITTER: Ruder AM 

PROVIDER: S-EPMC5511733 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature