A Click Chemistry Approach to Identify Protein Targets of Cancer Chemopreventive Phenethyl Isothiocyanate.

ABSTRACT: Here we report the identification of protein targets of chemopreventive phenethyl isothiocyanate (PEITC) via "click" chemistry in the A549 human lung cancer cell line, using a novel alkyne-tagged PEITC which was also found to show potent in vitro anticancer activity.

SUBMITTER: Fu Y 

PROVIDER: S-EPMC5512166 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature