The complementarity-determining region sequences in IgY antivenom hypervariable regions.

ABSTRACT: The data presented in this article are related to the research article entitled "Development of IgY antibodies against anti-snake toxins endowed with highly lethal neutralizing activity" (da Rocha et al., 2017) [1]. Complementarity-determining region (CDR) sequences are variable antibody (Ab) sequences that respond with specificity, duration and strength to identify and bind to antigen (Ag) epitopes. B lymphocytes isolated from hens immunized with Bitis arietans (Ba) and anti-Crotalus durissus terrificus (Cdt) venoms and expressing high specificity, affinity and toxicity neutralizing antibody titers were used as DNA sources. The VLF1, CDR1, CDR2, VLR1 and CDR3 sequences were validated by BLASTp, and values corresponding to IgY V_L and V_H anti-Ba or anti-C

SUBMITTER: da Rocha DG 

PROVIDER: S-EPMC5512210 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature