Detection of active transposable elements in Arabidopsis thaliana using Oxford Nanopore Sequencing technology.

ABSTRACT:

Background

Transposables elements (TEs) contribute to both structural and functional dynamics of most eukaryotic genomes. Because of their propensity to densely populate plant and animal genomes, the precise estimation of the impact of transposition on genomic diversity has been considered as one of the main challenges of today's genomics. The recent development of NGS (next generation sequencing) technologies has open new perspectives in population genomics by providing new methods for high throughput detection of Transposable Elements-associated Structural Variants (TEASV). However, these have relied on Illumina platform that generates short reads (up to 350 nucleotides). This limitation in size of sequence reads can cause high false discovery rate (FDR) and therefore limit the p

SUBMITTER: Debladis E 

PROVIDER: S-EPMC5513335 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature