DdRADseq reveals determinants for temperature-dependent sex reversal in Nile tilapia on LG23.

ABSTRACT:

Background

In Nile tilapia sex determination is governed by a male heterogametic system XX/XY either on LG1 or LG23. The latter carries a Y-specific duplicate of the amh gene, which is a testis-determining factor. Allelic variants in the amh gene demonstrated to be major triggers for autosomal and temperature-dependent sex reversal. Further, QTL on LG23 and LG20 show a temperature-responsiveness with influence on the phenotypic sex relative to the sex chromosomes. Here we present a ddRADseq based approach to identify genomic regions that show unusual large differentiation in terms of fixation index (F_ST) between temperature-treated pseudomales and non-masculinized females using a comparative genome-scan. Genome-wide associations were identified for the temperature-depend

SUBMITTER: Wessels S 

PROVIDER: S-EPMC5513378 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature