Patterns of care of brain tumor-related epilepsy. A cohort study done in Italian Epilepsy Center.

ABSTRACT: Epilepsy is the most common comorbidity in patients with brain tumors.

Study aims

To define characteristics of brain tumor-related epilepsy (BTRE) patients and identify patterns of care. Nationwide, multicenter retrospective cohort study. Medical records of BTRE patients seen from 1/1/2010 to 12/31/2011, followed for at least one month were examined. Information included age, sex, tumor type/treatments, epilepsy characteristics, antiepileptic drugs (AEDs). Time to modify first AED due to inefficacy and/or toxicity was assessed with the Kaplan-Meier method and Cox proportional hazard models were used to identify predictors of treatment outcome. Enrolled were 808 patients (447 men, 361 women) from 26 epilepsy centers. Follow-up ranged 1 to 423 months (median 18 months). 732 patients u

SUBMITTER: Maschio M 

PROVIDER: S-EPMC5513411 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature