Spectral Quantification for High-Resolution MR Spectroscopic Imaging With Spatiospectral Constraints.

ABSTRACT:

Objective

To obtain reliable spectral estimation from magnetic resonance spectroscopic imaging (MRSI) data.

Methods

The proposed method takes advantage of prior knowledge: 1) along the spectral dimension in the form of spectral bases, and 2) along the spatial dimensions in the form of spatial regularizations (e.g., smoothness or transform sparsity) and jointly estimates parameters from all the voxels.

Results

Simulation and in vivo studies have been performed to demonstrate the performance of the proposed method. A Cramér-Rao-bound-based analysis is also provided.

Conclusion

Incorporation of both spatial and spectral constraints can significantly improve spectral quantification of MRSI data.

Significance

The proposed method is expected to be useful for v

SUBMITTER: Ning Q 

PROVIDER: S-EPMC5513734 | biostudies-literature | 2017 May

REPOSITORIES: biostudies-literature