Investigating magnetic susceptibility of human knee joint at 7 Tesla.

ABSTRACT:

Purpose

To evaluate the magnetic susceptibility properties of different anatomical structures within the knee joint using quantitative susceptibility mapping (QSM).

Methods

A collagen tissue model was simulated and ex vivo animal cartilage experiments were conducted at 9.4 Tesla (T) to evaluate the B₀ orientation-dependent magnetic susceptibility contrast observed in cartilage. Furthermore, nine volunteers (six healthy subjects without knee pain history and three patients with known knee injury, between 29 and 58 years old) were scanned using gradient-echo acquisitions on a high-field 7T MR scanner. Susceptibility values of different tissues were quantified and diseased cartilage and meniscus were compared against that of healthy volunteers.

Results

Simulat

SUBMITTER: Wei H 

PROVIDER: S-EPMC5513801 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature