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Diagnosis of DWI-negative acute ischemic stroke: A meta-analysis.


ABSTRACT:

Objective

To determine the prevalence of diffusion-weighted imaging (DWI)-negative acute ischemic stroke (AIS) and to identify clinical characteristics of patients with DWI-negative AIS.

Methods

We systematically searched PubMed and Ovid/MEDLINE for relevant studies between 1992, the year that the DWI sequence entered clinical practice, and 2016. Studies were included based upon enrollment of consecutive patients presenting with a clinical diagnosis of AIS prior to imaging. Meta-analysis was performed to synthesize study-level data, estimate DWI-negative stroke prevalence, and estimate the odds ratios (ORs) for clinical characteristics associated with DWI-negative stroke.

Results

Twelve articles including 3,236 AIS patients were included. The meta-analytic synthesis y

SUBMITTER: Edlow BL 

PROVIDER: S-EPMC5513816 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature