Adjuvant radiation for salivary gland malignancies is associated with improved survival: A National Cancer Database analysis.

ABSTRACT:

Objective

There are no randomized data to support the use of postoperative radiation for salivary gland malignancies. This study uses the National Cancer Database (NCDB) to describe the epidemiology of salivary gland cancer patients and to investigate whether treatment with adjuvant radiation improves overall survival.

Methods and materials

A total of 8243 patients diagnosed with a major salivary gland cancer were identified from the NCDB. All patients received primary surgical resection of their malignancy. Patients were risk-stratified by adverse features, and overall survival rates were determined. Patients were considered high risk if they had extracapsular extension and/or positive margin after resection. Patients were considered intermediate risk if they did not meet t

SUBMITTER: Bakst RL 

PROVIDER: S-EPMC5514258 | biostudies-literature | 2017 Apr-Jun

REPOSITORIES: biostudies-literature