Multimodal Imaging in a Patient with Hemidystonia Responsive to GPi Deep Brain Stimulation.

ABSTRACT:

Background

Dystonia is a syndrome with varied phenomenology but our understanding of its mechanisms is deficient. With neuroimaging techniques, such as fiber tractography (FT) and magnetoencephalography (MEG), pathway connectivity can be studied to that end. We present a hemidystonia patient treated with deep brain stimulation (DBS).

Methods

After 10 years of left axial hemidystonia, a 45-year-old male underwent unilateral right globus pallidus internus (GPi) DBS. Whole brain MEG before and after anticholinergic medication was performed prior to surgery. 26-direction diffusion tensor imaging (DTI) was obtained in a 3 T MRI machine along with FT. The patient was assessed before and one year after surgery by using the Burke-Fahn-Marsden Dystonia Rating Scale (BFMDRS).

Resul

SUBMITTER: Sidiropoulos C 

PROVIDER: S-EPMC5514339 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature