Phylogenic analysis of human bocavirus detected in children with acute respiratory infection in Yaounde, Cameroon.

ABSTRACT:

Objective

Human Bocavirus (HBoV) was first identified in 2005 and has been shown to be a common cause of respiratory infections and gastroenteritis in children. In a recent study, we found that 10.7% of children with acute respiratory infections (ARI) were infected by HBoV. Genetic characterization of this virus remains unknown in Central Africa, particularly in Cameroon Leeding us to evaluate the molecular characteristics of HBoV strains in Cameroonian children with ARI.

Results

Phylogenetic analysis of partial HBoV VP1/2 sequences showed a low level of nucleotide variation and the circulation of HBoV genotype 1 (HBoV-1) only. Three clades were obtained, two clustering with each of the reference strains ST1 and ST2, and a third group consisting of only Cameroon strains. By

SUBMITTER: Kenmoe S 

PROVIDER: S-EPMC5514512 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature