Prevalence of allergic rhinitis and asthma in patients with chronic rhinosinusitis and gastroesophageal reflux disease.

ABSTRACT:

Background

An association between chronic rhinosinusitis (CRS) and gastroesophageal reflux disease (GERD) has been previously reported; however, the underlying factors linking CRS and GERD remain to be elucidated.

Objective

To assess the association of GERD and CRS using prospective and retrospective approaches.

Methods

The retrospective study comprised a large cohort of CRS cases, whereas the prospective arm evaluated a series of CRS cases and controls.

Results

In the retrospective arm of the study, of the 1066 patients with CRS, 112 (10.5%) had GERD. Among patients with CRS, GERD was associated with higher body mass index, older age, and female sex. The odds ratios (ORs) for asthma and allergic rhinitis in the CRS group with GERD compared with the CRS group w

SUBMITTER: Mahdavinia M 

PROVIDER: S-EPMC5514562 | biostudies-literature | 2016 Aug

REPOSITORIES: biostudies-literature