Phosphosite charge rather than shootward localization determines OCTOPUS activity in root protophloem.

ABSTRACT: Polar cellular localization of proteins is often associated with their function and activity. In plants, relatively few polar-localized factors have been described. Among them, the plasma membrane-associated Arabidopsis proteins OCTOPUS (OPS) and BREVIS RADIX (BRX) display shootward and rootward polar localization, respectively, in developing root protophloem cells. Both ops and brx null mutants exhibit defects in protophloem differentiation. Here we show that OPS and BRX act genetically in parallel in this process, although OPS dosage increase mends defects caused by brx loss-of-function. OPS protein function is ancient and conserved in the most basal angiosperms; however, many highly conserved structural OPS features are not strictly requi

SUBMITTER: Breda AS 

PROVIDER: S-EPMC5514738 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature