Interfacing peripheral nerve with macro-sieve electrodes following spinal cord injury.

ABSTRACT: Macro-sieve electrodes were implanted in the sciatic nerve of five adult male Lewis rats following spinal cord injury to assess the ability of the macro-sieve electrode to interface regenerated peripheral nerve fibers post-spinal cord injury. Each spinal cord injury was performed via right lateral hemisection of the cord at the T_9-10 site. Five months post-implantation, the ability of the macro-sieve electrode to interface the regenerated nerve was assessed by stimulating through the macro-sieve electrode and recording both electromyography signals and evoked muscle force from distal musculature. Electromyography measurements were recorded from the tibialis anterior and gastrocnemius muscles, while evoked muscle force measurements were recorded from the tibialis anterior,

SUBMITTER: Birenbaum NK 

PROVIDER: S-EPMC5514861 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature