3D-accelerated, stack-of-spirals acquisitions and reconstruction of arterial spin labeling MRI.

ABSTRACT:

Purpose

The goal of this study was to develop a 3D acceleration and reconstruction method to improve image quality and resolution of background-suppressed arterial spin-labeled perfusion MRI.

Methods

Accelerated acquisition was implemented in all three k-space dimensions in a stack-of-spirals readout using variable density spirals and partition undersampling. A single 3D self-consistent parallel imaging (SPIRiT) kernel was calibrated and iteratively applied to reconstruct each imaging volume. Whole-brain (including cerebellum) perfusion imaging was obtained at 3-mm isotropic resolution (nominal) using single- and 2-shot acquisitions and at 2-mm isotropic resolution (nominal) using four-shot acquisitions, achieving effective acceleration factors between 5.5 and 6.6. The signa

SUBMITTER: Chang YV 

PROVIDER: S-EPMC5515691 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature