Picture free recall performance linked to the brain's structural connectome.

ABSTRACT:

Introduction

Memory functions are highly variable between healthy humans. The neural correlates of this variability remain largely unknown.

Methods

Here, we investigated how differences in free recall performance are associated with DTI-based properties of the brain's structural connectome and with grey matter volumes in 664 healthy young individuals tested in the same MR scanner.

Results

Global structural connectivity, but not overall or regional grey matter volumes, positively correlated with recall performance. Moreover, a set of 22 inter-regional connections, including some with no previously reported relation to human memory, such as the connection between the temporal pole and the nucleus accumbens, explained 7.8% of phenotypic variance.

Conclusions

In co

SUBMITTER: Coynel D 

PROVIDER: S-EPMC5516597 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature