Diazepam Is No Better Than Placebo When Added to Naproxen for Acute Low Back Pain.

ABSTRACT:

Study objective

Low back pain causes more than 2.5 million visits to US emergency departments (EDs) annually. Low back pain patients are often treated with nonsteroidal anti-inflammatory drugs and benzodiazepines. The former is an evidence-based intervention, whereas the efficacy of the latter has not been established. We compare pain and functional outcomes 1 week and 3 months after ED discharge among patients randomized to a 1-week course of naproxen+diazepam versus naproxen+placebo.

Methods

This was a randomized, double-blind, comparative efficacy clinical trial conducted in an urban health care system. Patients presenting with acute, nontraumatic, nonradicular low back pain of no more than a duration of 2 weeks were eligible for enrollment immediately before discharge fr

SUBMITTER: Friedman BW 

PROVIDER: S-EPMC5517351 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature