CrossCheck: an open-source web tool for high-throughput screen data analysis.

ABSTRACT: Modern high-throughput screening methods allow researchers to generate large datasets that potentially contain important biological information. However, oftentimes, picking relevant hits from such screens and generating testable hypotheses requires training in bioinformatics and the skills to efficiently perform database mining. There are currently no tools available to general public that allow users to cross-reference their screen datasets with published screen datasets. To this end, we developed CrossCheck, an online platform for high-throughput screen data analysis. CrossCheck is a centralized database that allows effortless comparison of the user-entered list of gene symbols with 16,231 published datasets. These datasets include published data from genome-wide RNAi and CRISPR screens

SUBMITTER: Najafov J 

PROVIDER: S-EPMC5517520 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature