Factors controlling the reactivity of divalent metal ions towards pheophytin a.

ABSTRACT: In this study, we evaluate the factors which determine the reactivity of divalent metal ions in the spontaneous formation of metallochlorophylls, using experimental and computational approaches. Kinetic studies were carried out using pheophytin a in reactions with various divalent metal ions combined with non- or weakly-coordinative counter ions in a series of organic solvents. To obtain detailed insights into the solvent effect, the metalations with the whole set of cations were investigated in three solvents and with Zn²⁺ in seven solvents. The reactions were monitored using electronic absorption spectroscopy and the stopped-flow technique. DFT calculations were employed to shed light on the role of solvent in activating the metal ions towards porphyrinoids. This experimental

SUBMITTER: Orzel L 

PROVIDER: S-EPMC5517585 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature