Factors associated with falling in early, treated Parkinson's disease: The NET-PD LS1 cohort.

ABSTRACT:

Background

Recognizing the factors associated with falling in Parkinson's disease (PD) would improve identification of at-risk individuals.

Objective

To examine frequency of falling and baseline characteristics associated with falling in PD using the National Institute of Neurological Disorders and Stroke (NINDS) Exploratory Trials in PD Long-term Study-1 (NET-PD LS-1) dataset.

Methods

The LS-1 database included 1741 early treated PD subjects (median 4year follow-up). Baseline characteristics were tested for a univariate association with post-baseline falling during the trial. Significant variables were included in a multivariable logistic regression model. A separate analysis using a negative binomial model investigated baseline factors on fall rate.

Results

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SUBMITTER: Chou KL 

PROVIDER: S-EPMC5518305 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature