Geographic strain differentiation of Schistosoma japonicum in the Philippines using microsatellite markers.

ABSTRACT:

Background

Microsatellites have been found to be useful in determining genetic diversities of various medically-important parasites which can be used as basis for an effective disease management and control program. In Asia and Africa, the identification of different geographical strains of Schistosoma japonicum, S. haematobium and S. mansoni as determined through microsatellites could pave the way for a better understanding of the transmission epidemiology of the parasite. Thus, the present study aims to apply microsatellite markers in analyzing the populations of S. japonicum from different endemic areas in the Philippines for possible strain differentiation.

Methodology/ principal findings

Experimental mice were infected using the cercariae of S. japonicum collected from

SUBMITTER: Moendeg KJ 

PROVIDER: S-EPMC5519200 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature