Neural determinants of human goal-directed vs. habitual action control and their relation to trait motivation.

ABSTRACT: Instrumental learning is mediated by goal-directed and habit systems in the brain. While rodent studies implicate distinct prefrontal/striatal regions in goal-directed and habit learning, neural systems underpinning these two processes in humans remain poorly understood. Here, using a validated discrimination learning task that distinguishes goal-directed learning from habit learning in 72 subjects in fMRI, we investigated the corticostriatal correlates of goal-directed learning and tested whether brain activation during learning is associated with trait motivation and behavioral performance in the post-learning test phase. Participants showed enhanced activation in medial prefrontal and posterior cingulate cortices during goal-directed action selection in the training phase, whereas habit

SUBMITTER: Eryilmaz H 

PROVIDER: S-EPMC5519538 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature