Methodology for non-target screening of sewage sludge using comprehensive two-dimensional gas chromatography coupled to high-resolution mass spectrometry.

ABSTRACT: To investigate the wide range of pollutants occurring in sewage sludge, an analytical method for comprehensive non-target screening is needed. To the best of our knowledge, no procedures currently exist for the full screening of organic contaminants in sewage sludge, which is the ultimate goal of this project. We developed non-discriminating sample preparation methods for gas chromatography-mass spectrometry (GC-MS) analysis. Pressurized liquid extraction (PLE) was used for extraction, with in-line (silica gel selective PLE, SPLE) or off-line clean-up (gel permeation chromatography, GPC). This combination allowed the analysis of non-polar compounds of all sizes and small semi-polar and non-polar compounds. The results show that the combination of SPLE and PLE with GPC is suitable for analy

SUBMITTER: Veenaas C 

PROVIDER: S-EPMC5519657 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature