Common Brain Structure Findings Across Children with Varied Reading Disability Profiles.

ABSTRACT: Dyslexia is a developmental disorder in reading that exhibits varied patterns of expression across children. Here we examined the degree to which different kinds of reading disabilities (defined as profiles or patterns of reading problems) contribute to brain morphology results in Jacobian determinant images that represent local brain shape and volume. A matched-pair brain morphometry approach was used to control for confounding from brain size and research site effects in this retrospective multi-site study of 134 children from eight different research sites. Parietal operculum, corona radiata, and internal capsule differences between cases and controls were consistently observed across children with evidence of classic dyslexia, specific comprehension deficit, and language learning disab

SUBMITTER: Eckert MA 

PROVIDER: S-EPMC5519686 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature