Implementing precision cancer medicine in the public health services of Norway: the diagnostic infrastructure and a cost estimate.

ABSTRACT:

Objective

Through the conduct of an individual-based intervention study, the main purpose of this project was to build and evaluate the required infrastructure that may enable routine practice of precision cancer medicine in the public health services of Norway, including modelling of costs.

Methods

An eligible patient had end-stage metastatic disease from a solid tumour. Metastatic tissue was analysed by DNA sequencing, using a 50-gene panel and a study-generated pipeline for analysis of sequence data, supplemented with fluorescence in situ hybridisation to cover relevant biomarkers. Cost estimations compared best supportive care, biomarker-agnostic treatment with a molecularly targeted agent and biomarker-based treatment with such a drug. These included costs for medicatio

SUBMITTER: Ree AH 

PROVIDER: S-EPMC5519811 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature