Genome-wide signals of positive selection in strongylocentrotid sea urchins.

ABSTRACT:

Background

Comparative genomics studies investigating the signals of positive selection among groups of closely related species are still rare and limited in taxonomic breadth. Such studies show great promise in advancing our knowledge about the proportion and the identity of genes experiencing diversifying selection. However, methodological challenges have led to high levels of false positives in past studies. Here, we use the well-annotated genome of the purple sea urchin, Strongylocentrotus purpuratus, as a reference to investigate the signals of positive selection at 6520 single-copy orthologs from nine sea urchin species belonging to the family Strongylocentrotidae paying careful attention to minimizing false positives.

Results

We identified 1008 (15.5%) candidate posit

SUBMITTER: Kober KM 

PROVIDER: S-EPMC5521101 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature