Estimation of linkage disequilibrium and effective population size in New Zealand sheep using three different methods to create genetic maps.

ABSTRACT:

Background

Investments in genetic selection have played a major role in the New Zealand sheep industry competitiveness. Selection may erode genetic diversity, which is a crucial factor for the success of breeding programs. Better understanding of linkage disequilibrium (LD) and ancestral effective population size (N_e) through quantifying this diversity and comparison between populations allows for more informed decisions with regards to selective breeding taking population genetic diversity into account. The estimation of N _e can be determined via genetic markers and requires knowledge of genetic distances between these markers. Single nucleotide polymorphisms (SNP) data from a sample of 12,597 New Zealand crossbred and purebred sheep genotyped with the Illumi

SUBMITTER: Prieur V 

PROVIDER: S-EPMC5521107 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature