Ultrasonography and dual-energy computed tomography provide different quantification of urate burden in gout: results from a cross-sectional study.

ABSTRACT:

Background

Ultrasonography (US) and dual-energy computed tomography (DECT) can assess urate burden in gout. The objective of this study was to compare the quantification of urate deposition provided by US to the one provided by DECT.

Methods

Patients with a diagnosis of gout were prospectively recruited to undergo quantification of urate deposition using US and DECT. US examination for tophi and the double contour (DC) sign was performed on the knees and feet and corresponding DECT scans provided volumes of tophi and of overall urate deposition. The primary endpoint was the intra-class correlation coefficient (ICC) of the volume of the index tophus measured by US and DECT and its 95% confidence interval (CI 95%).

Results

Of the 64 patients included, 34 presented with

SUBMITTER: Pascart T 

PROVIDER: S-EPMC5521183 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature