Computed tomographic perfusion to Predict Response to Recanalization in ischemic stroke.

ABSTRACT:

Objective

To assess the utility of computed tomographic (CT) perfusion for selection of patients for endovascular therapy up to 18 hours after symptom onset.

Methods

We conducted a multicenter cohort study of consecutive acute stroke patients scheduled to undergo endovascular therapy within 90 minutes after a baseline CT perfusion. Patients were classified as "target mismatch" if they had a small ischemic core and a large penumbra on their baseline CT perfusion. Reperfusion was defined as >50% reduction in critical hypoperfusion between the baseline CT perfusion and the 36-hour follow-up magnetic resonance imaging.

Results

Of the 201 patients enrolled, 190 patients with an adequate baseline CT perfusion study who underwent angiography were included (mean age = 66 year

SUBMITTER: Lansberg MG 

PROVIDER: S-EPMC5521988 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature