Heart failure and risk of dementia: a Danish nationwide population-based cohort study.

ABSTRACT:

Aims

The association between heart failure and dementia remains unclear. We assessed the risk of dementia among patients with heart failure and members of a general population comparison cohort.

Methods and results

Individual-level data from Danish medical registries were linked in this nationwide population-based cohort study comparing patients with a first-time hospitalization for heart failure between 1980 and 2012 and a year of birth-, sex-, and calendar year-matched comparison cohort from the general population. Stratified Cox regression analysis was used to compute 1-35-year hazard ratios (HRs) for the risk of all-cause dementia and, secondarily, Alzheimer's disease, vascular dementia, and other dementias. Analyses included 324 418 heart failure patients and 1 622 079

SUBMITTER: Adelborg K 

PROVIDER: S-EPMC5522185 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature