Evaluation of serum cytokines in cats with and without degenerative joint disease and associated pain.

ABSTRACT: Degenerative joint disease is common in cats, with signs of pain frequently found on orthopedic examination and radiographs often showing evidence of disease. However, understanding of the pathophysiology of degenerative joint disease and associated pain remains limited. Several cytokines have been identified as having a role in pain in humans, but this has not been investigated in cats. The present study was performed to use a multiplex platform to evaluate the concentration of 19 cytokines and chemokines in serum samples obtained from cats with and without degenerative joint disease and associated pain. Samples from a total of 186 cats were analyzed, with cats representing a range of severity on radiographic and orthopedic evaluations and categorized by degenerative joint disease scores

SUBMITTER: Gruen ME 

PROVIDER: S-EPMC5522727 | biostudies-literature | 2017 Jan

REPOSITORIES: biostudies-literature