Measures of Kidney Disease and the Risk of Venous Thromboembolism in the REGARDS (Reasons for Geographic and Racial Differences in Stroke) Study.

ABSTRACT:

Background

Kidney disease has been associated with venous thromboembolism (VTE) risk, but results conflict and there is little information regarding blacks.

Study design

Prospective cohort study.

Setting & participants

30,239 black and white adults 45 years or older enrolled in the REGARDS (Reasons for Geographic and Racial Differences in Stroke) Study 2003 to 2007.

Predictors

Estimated glomerular filtration rate (eGFR) using the combined creatinine-cystatin C (eGFR_cr-cys) equation and urinary albumin-creatinine ratio (ACR).

Outcomes

The primary outcome was adjudicated VTE, and secondary outcomes were provoked and unprovoked VTE, separately. Mortality was a competing-risk event.

Results

During 4.6 years of follow-up, 239 incident VTE ev

SUBMITTER: Cheung KL 

PROVIDER: S-EPMC5522772 | biostudies-literature | 2017 Aug

REPOSITORIES: biostudies-literature